Microbiota-dependent Early-life Programming of Gastrointestinal Motility

Gastrointestinal microbes modulate peristalsis and stimulate the enteric nervous system (ENS), whosedevelopment, as in the central nervous system (CNS), continues into the murine postweaning period.Given that adult CNS function depends on stimuli received during critical periods of postnatal development, we hypothesized that adult ENS function, namely motility, depends on microbial stimuli during similar critical periods. […]

UChicago Microbiome Startups Come Together Under New Company to Amplify Results

A colorful graphic depicting the gut microbiome.

Two University of Chicago startups are now operating under a parent company, 32 Biosciences – with a shared goal to revolutionize health care through advances in microbiome science. The name is pronounced “three squared biosciences” in homage to its three scientific founders and microbiome medicine experts: University of Chicago professors John Alverdy and Eugene Chang, and assistant professor […]

32 Biosciences Emerges from Stealth Mode with New Approach to Gut Microbiome Medicine

Roslyn Franklin Research Building Rendering

32 Biosciences, pronounced “Three Squared Biosciences,” proudly announces its emergence from stealth mode, with new microbiome diagnostic management tools and microbiome-based interventions. The company intends to revolutionize healthcare with its novel approach to gut microbiome medicine. 32 Biosciences Emerges from Stealth Mode with New Approach to Gut Microbiome Medicine,” published on PR Newswire on January […]

Preventing Surgical Site Infections in the Era of Escalating Antibiotic Resistance and Antibiotic Stewardship

Importance: According to the Centers for Disease Control and Prevention and governing bodies within the American College of Surgeons, the administration of antibiotics as prophylaxis against infection prior to a planned elective procedure is, with rare exception, routinely recommended. The goal of “getting to zero” infections remains a high priority for policymakers, practitioners, and certainly for […]