Microbiota-dependent Early-life Programming of Gastrointestinal Motility

Gastrointestinal microbes modulate peristalsis and stimulate the enteric nervous system (ENS), whose development, as in the central nervous system (CNS), continues into the murine postweaning period.Given that adult CNS function depends on stimuli received during critical periods of postnatal development, we hypothesized that adult ENS function, namely motility, depends on microbial stimuli during similar critical […]

UChicago Microbiome Startups Come Together Under New Company to Amplify Results

A colorful graphic depicting the gut microbiome.

Two University of Chicago startups are now operating under a parent company, 32 Biosciences – with a shared goal to revolutionize health care through advances in microbiome science. The name is pronounced “three squared biosciences” in homage to its three scientific founders and microbiome medicine experts: University of Chicago professors John Alverdy and Eugene Chang, and assistant professor […]